CSTI-300 (SMP-100); a Novel 5-HT3Receptor Partial Agonist with Potential to Treat Patients with Irritable Bowel Syndrome or Carcinoid Syndrome
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چکیده
منابع مشابه
Diets and Irritable Bowel Syndrome
Introduction: Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder, which is characterized by the presence of abdominal pain or discomfort associated with altered bowel habits. This systematic review aimed to assess the nutritional factors (dietary patterns and food groups) associated with IBS. Methods: Articles were collected ...
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Abstract Background and objectives: Irritable bowel syndrome (IBS) is one of the most common gastrointestinal diseases. It is a functional bowel disorder characterized by chronic abdominal pain and alternation of bowel habits with no structural abnormality. The prevalence of this disease was estimated 10-20 percent in the world. However, the cause of IBS is still unknown. Regarding to int...
متن کاملApproaching patients with irritable bowel syndrome
Treatment of functional gastrointestinal disorders remains difficult with many very different approaches showing similar response rates, regardless of whether they target luminal contents (e.g., presumed bacterial overgrowth), signaling within the gut wall (e.g., serotonin agonists or antagonists) or processing in the brain (e.g., cognitive behavioral therapy). Discrepancies between recent clin...
متن کاملGhrelin in patients with irritable bowel syndrome.
General gastrointestinal dysmotility occurs in patients with irritable bowel syndrome (IBS). Ghrelin seems to play an important role in regulating gastrointestinal motility. The present study was undertaken, therefore, to establish the possible role of ghrelin in the pathophysiology of IBS. Thirty-seven patients with IBS (19 had IBS-constipation and 18 IBS-diarrhoea) were included in this study...
متن کاملSeroprevalence of Campylobacter Jejuni in Patients with Irritable Bowel Syndrome and in Healthy Individuals
Abstract Background and Objective: The patients with Post-Infectious Irritable bowel syndrome (PI-IBS), a subtype of irritable bowel syndrome, suffer from bacterial gastroenteritis. Since campylobacter Jejuni (CJ) is one of the most common agents in this syndrome, we aimed to evaluate the prevalence of Campylobacter Jejuni in patients with Irritable Bowel Disease. Material and Methods: Th...
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ژورنال
عنوان ژورنال: Journal of Pharmacology and Experimental Therapeutics
سال: 2020
ISSN: 0022-3565,1521-0103
DOI: 10.1124/jpet.119.261008